Mayoreak Ashoona was born in 1946 in Saturituk, a small camp on southern Baffin Island. She was married to Kaka Ashoona, the late notable carver and son of Pitseolak Ashoona. After Kaka's death, Mayoreak and her children moved to Cape Dorset.
She began drawing in 1963 and is known for her imaginative and highly colored graphics. She has been consistently represented in the Annual Print collections from Cape Dorset since her work was first published in 1978. She has also developed quite a reputation as a master carver.
Mayoreak has contributed to exhibitions presented in Canada, Germany and Japan. In 1986 she took part in an exhibition entitled "Northern Exposure: Inuit Images of Travel", organized by the Burnaby (BC) Art Gallery along with the Department of Northern Development and the Government of the Northwest Territories. She was one of the selected feature artists in the acclaimed exhibition "Isumavut: The Artistic Expression of Nine Cape Dorset Women", which opened at the Canadian Museum of Civilization in the fall of 1994.
Mayoreak lives in Cape Dorset with her family and continues to participate in workshops offered by the Kinngait Studios but much of her energy in recent years has been devoted to carving.